MOPA — Medical Oncology Prior Authorization - Local Development build (v0.1.1-snapshot-080926) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
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<PlanDefinition xmlns="http://hl7.org/fhir">
<id value="RegimenPHD"/>
<meta>
<profile
value="http://hl7.org/fhir/us/codex-mopa/StructureDefinition/anticancer-regimen-plandefinition"/>
</meta>
<language value="en"/>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml">
<table class="narrative-table">
<tbody>
<tr>
<th colspan="2" scope="row" class="row-header">Metadata</th>
</tr>
<tr>
<th scope="row" class="row-header">Title</th>
<td class="content-container">PHD: Pertuzumab + Trastuzumab + Docetaxel — Metastatic HER2+ Breast Cancer</td>
</tr>
<tr>
<th scope="row" class="row-header">Version</th>
<td class="content-container">0.1.1-snapshot-080926</td>
</tr>
<tr>
<th scope="row" class="row-header">Experimental</th>
<td class="content-container">true</td>
</tr>
<tr>
<th scope="row" class="row-header">Subject Type</th>
<td class="content-container">
Malignant neoplasm of breast
</td>
</tr>
<tr>
<th scope="row" class="row-header">Jurisdiction</th>
<td class="content-container">
United States of America
</td>
</tr>
<tr>
<th scope="row" class="row-header">Steward (Publisher)</th>
<td class="content-container">HL7 International / Clinical Interoperability Council</td>
</tr>
<tr>
<th scope="row" class="row-header">Steward Contact</th>
<td class="content-container">HL7 International / Clinical Interoperability Council</td>
</tr>
<tr>
<th scope="row" class="row-header">Description</th>
<td class="content-container"><div><p>PHD regimen every 21 days for HER2+ metastatic breast cancer. Standard of care per CLEOPATRA trial.</p>
</div></td>
</tr>
<tr>
<th scope="row" class="row-header">Type</th>
<td class="content-container">
Order Set
</td>
</tr>
<tr>
<th colspan="2" scope="row" class="row-header">PlanDefinition Action</th>
</tr>
<tr>
<th scope="row" class="row-header">Id</th>
<td class="content-container">pertuzumab-phd</td>
</tr>
<tr>
<th scope="row" class="row-header">Title</th>
<td class="content-container">Pertuzumab 840 mg IV (cycle 1), then 420 mg IV q21d</td>
</tr>
<tr>
<th scope="row" class="row-header">Timing</th>
<td class="content-container">Once per 21 days</td>
</tr>
<tr>
<th colspan="2" scope="row" class="row-header">PlanDefinition Action</th>
</tr>
<tr>
<th scope="row" class="row-header">Id</th>
<td class="content-container">trastuzumab-phd</td>
</tr>
<tr>
<th scope="row" class="row-header">Title</th>
<td class="content-container">Trastuzumab 8 mg/kg IV (cycle 1), then 6 mg/kg IV q21d</td>
</tr>
<tr>
<th scope="row" class="row-header">Timing</th>
<td class="content-container">Once per 21 days</td>
</tr>
<tr>
<th colspan="2" scope="row" class="row-header">PlanDefinition Action</th>
</tr>
<tr>
<th scope="row" class="row-header">Id</th>
<td class="content-container">docetaxel-phd</td>
</tr>
<tr>
<th scope="row" class="row-header">Title</th>
<td class="content-container">Docetaxel 75 mg/m² IV — Day 1 of each 21-day cycle</td>
</tr>
<tr>
<th scope="row" class="row-header">Timing</th>
<td class="content-container">Once per 21 days</td>
</tr>
<tr>
<th colspan="2" scope="row" class="row-header">Generated using version 0.5.4 of the sample-content-ig Liquid templates</th>
</tr>
</tbody>
</table>
</div>
</text>
<url value="http://hl7.org/fhir/us/codex-mopa/PlanDefinition/RegimenPHD"/>
<version value="0.1.1-snapshot-080926"/>
<name value="RegimenPHD"/>
<title
value="PHD: Pertuzumab + Trastuzumab + Docetaxel — Metastatic HER2+ Breast Cancer"/>
<type>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
<code value="order-set"/>
<display value="Order Set"/>
</coding>
</type>
<status value="active"/>
<experimental value="true"/>
<subjectCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="254837009"/>
<display value="Malignant neoplasm of breast"/>
</coding>
</subjectCodeableConcept>
<date value="2026-09-08T18:17:28-04:00"/>
<publisher value="HL7 International / Clinical Interoperability Council"/>
<contact>
<name value="HL7 International / Clinical Interoperability Council"/>
<telecom>
<system value="url"/>
<value value="http://www.hl7.org/Special/committees/cic"/>
</telecom>
<telecom>
<system value="email"/>
<value value="ciclist@lists.HL7.org"/>
</telecom>
</contact>
<description
value="PHD regimen every 21 days for HER2+ metastatic breast cancer. Standard of care per CLEOPATRA trial."/>
<jurisdiction>
<coding>
<system value="urn:iso:std:iso:3166"/>
<code value="US"/>
<display value="United States of America"/>
</coding>
</jurisdiction>
<action id="pertuzumab-phd">
<title value="Pertuzumab 840 mg IV (cycle 1), then 420 mg IV q21d"/>
<timingTiming>
<repeat>
<period value="21"/>
<periodUnit value="d"/>
</repeat>
</timingTiming>
</action>
<action id="trastuzumab-phd">
<title value="Trastuzumab 8 mg/kg IV (cycle 1), then 6 mg/kg IV q21d"/>
<timingTiming>
<repeat>
<period value="21"/>
<periodUnit value="d"/>
</repeat>
</timingTiming>
</action>
<action id="docetaxel-phd">
<title value="Docetaxel 75 mg/m² IV — Day 1 of each 21-day cycle"/>
<timingTiming>
<repeat>
<period value="21"/>
<periodUnit value="d"/>
</repeat>
</timingTiming>
</action>
</PlanDefinition>